Courage, trust, and taking risks, what’s love got to do with it? A chance reunion between Kikay (Angelica Panganiban) and her childhood buddy Kiko (Jason Abalos) ushers in a powerful attraction that Kiko welcomes but Mitch resists out of her haunting past mistakes. Boyish kalesa driver Badong (Anne Curtis) catches the attention of wealthy ladies'' man Wesley (Luis Manzano) but she feels disinclined to indulge him and herself because they belong to different social classes. In her desperation to prove that true love exists, Lia (Bea Alonzo) searches for the owner of a tape containing the voice of a man professing his deep affection and ends up with the least likely person to own it: her uncouth and obnoxious neighbor Eric (John Lloyd Cruz). Six people whose lives become intertwined by their common need for significance, bet big, risk everything, and learn life lessons -- lessons that happen to be all about love.